Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9217598 | 0.99 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9221753 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9211090 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9209645 | 0.79 | HTR2A (0.52) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL9212810 | 0.78 | HTR2A (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL9212821 | 0.78 | HTR2A (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL9213650 | 0.78 | HTR2A (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9214012 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL13452487 | 0.72 | DRD4 (0.60) | HRH3 | |
| Hydrochloric Acid SCHEMBL9211654 | 0.70 | HTR2A (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | claimed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | claimed |
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |