Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.67 |
| ▸ | DRD2 | P14416 | 9/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9213499 | 0.99 | HTR1A (0.66) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9206679 | 0.97 | HTR1A (0.63) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9213179 | 0.93 | HTR2A (0.60) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9214057 | 0.92 | HTR2A (0.58) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9213108 | 0.87 | HTR1A (0.69) | HTR1ADRD2HTR7 | |
| SCHEMBL9207116 | 0.84 | HTR1A (0.63) | HTR1ADRD2 | |
| SCHEMBL9208142 | 0.83 | HTR1A (0.48) | HTR1ADRD2 | |
| SCHEMBL9206746 | 0.82 | HTR1A (0.58) | HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9207791 | 0.81 | HTR1A (0.60) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11824808 | 0.81 | HTR1A (0.76) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345808-B1 | 1-Indolylalkyl-4-(substituted-pyridinyl)piperazines | BRISTOL MYERS SQUIBB CO (US) | 1995-01-11 | — | — | EP | claimed |
| US-4954502-A | Antidepressants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-09-04 | — | — | US | claimed |
| EP-0345808-A1 | 1-Indolylalkyl-4-(substituted-pyridinyl)piperazines | Bristol-Myers Squibb Company (US) | 1989-12-13 | — | — | EP | claimed |