Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202013 | 0.80 | THRA (0.48) | — | |
| SCHEMBL9212008 | 0.80 | ELANE (0.41) | ELANEPPARGPPARASMN1; SMN2MAPT | |
| SCHEMBL9211999 | 0.71 | HDAC3 (0.42) | PPARGPPARASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9825038 | 0.68 | POLB (0.50) | ALDH1A1LMNARAB9AHPGDHDAC1 | |
| SCHEMBL14010834 | 0.66 | L3MBTL1 (0.56) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL14010836 | 0.66 | L3MBTL1 (0.56) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL165545 | 0.66 | L3MBTL1 (0.48) | SMN1; SMN2LMNAMAPTNPC1RAB9A | |
| SCHEMBL19955336 | 0.65 | ABCB1 (0.44) | NPC1RAB9AMEN1KMT2AHDAC3 | |
| SCHEMBL2683319 | 0.65 | ABCB1 (0.44) | NPC1RAB9AMEN1KMT2AHDAC3 | |
| SCHEMBL908522 | 0.65 | KDM4E (0.68) | ELANEALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415256-B1 | Mesomorphic compound, liquid crystal composition containing same and liquid crystal device using same | CANON KK (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5091109-A | Ferroelectric; improved responsiveness | CANON KABUSHIKI KAISHA (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0415256-A2 | Mesomorphic compound, liquid crystal composition containing same and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1991-03-06 | — | — | EP | disclosed |