Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 9/20 | 0.31 |
| ▸ | BCHE | P06276 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219614 | 0.83 | ACHE (0.30) | ACHEBCHE | |
| SCHEMBL9212163 | 0.79 | ACHE (0.38) | SMYD3ACHEBCHE | |
| SCHEMBL9852507 | 0.78 | SMN1; SMN2 (0.41) | ACHEBCHE | |
| SCHEMBL9219510 | 0.74 | HRH3 (0.31) | — | |
| SCHEMBL9215498 | 0.74 | HRH3 (0.34) | — | |
| SCHEMBL9218010 | 0.71 | HRH3 (0.34) | — | |
| SCHEMBL9213764 | 0.70 | HTT (0.36) | — | |
| SCHEMBL9212791 | 0.70 | PRKCQ (0.30) | — | |
| SCHEMBL9217518 | 0.67 | — | — | |
| SCHEMBL9219620 | 0.63 | ACHE (0.34) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413343-B1 | Furan derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |