SCHEMBL9219620

SCHEMBL9219620

CN(C)Cc1ccc(CNCCN2CCNC2=C(C#N)C#N)o1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 12/20 0.34
BCHE P06276 8/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852543 0.91 SCN9A (0.30)
SCHEMBL9215512 0.90 LMNA (0.32)
SCHEMBL9219515 0.89 SCN9A (0.32) ACHE
SCHEMBL9217125 0.84 ACHE (0.46) ACHE
SCHEMBL9212163 0.84 ACHE (0.38) ACHEBCHE
SCHEMBL9218033 0.83 ACHE (0.47) ACHE
SCHEMBL9218017 0.83 ACHE (0.47) ACHE
SCHEMBL9213773 0.82 ACHE (0.38) ACHE
SCHEMBL9217083 0.82 ACHE (0.36) ACHE
SCHEMBL9212797 0.82 ACHE (0.38) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413343-B1 Furan derivatives KYOWA HAKKO KOGYO KK (JP) 1995-08-02 EP disclosed
US-5075301-A FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS KYOWA HAKKO KOGYO, CO., LTD. (JP) 1991-12-24 US disclosed
EP-0413343-A2 Furan derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-02-20 EP disclosed