Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212219 | 1.00 | GPR84 (0.39) | GPR84MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7496845 | 0.90 | MMP1 (0.43) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7496842 | 0.90 | MMP1 (0.43) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7495637 | 0.86 | GAA (0.52) | KMT2AALDH1A1GAAPOLBHTT | |
| SCHEMBL7495641 | 0.86 | GAA (0.52) | KMT2AALDH1A1GAAPOLBHTT | |
| SCHEMBL13879515 | 0.68 | HDAC1 (0.69) | MEN1KMT2AALDH1A1GAAPOLB | |
| SCHEMBL7492804 | 0.66 | CAPN1 (0.40) | MEN1KMT2AMAPTGAACAPN1 | |
| SCHEMBL7492801 | 0.66 | CAPN1 (0.40) | MEN1KMT2AMAPTGAACAPN1 | |
| SCHEMBL8291943 | 0.65 | GAA (0.84) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL873923 | 0.65 | HDAC6 (0.62) | MEN1KMT2AMAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |