Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.31 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209434 | 0.87 | NR1I2 (0.52) | NR1I2CYP3A4CYP2D6MAPK14 | |
| SCHEMBL9207040 | 0.84 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6PPARAS1PR1 | |
| SCHEMBL10415052 | 0.83 | PPARA (0.34) | PPARA | |
| SCHEMBL9212415 | 0.82 | NR1I2 (0.56) | NR1I2CYP3A4CYP2D6MAPK14SCARB1 | |
| SCHEMBL9201720 | 0.82 | CYP3A4 (0.52) | NR1I2CYP3A4CYP2D6PPARAS1PR1 | |
| SCHEMBL9205000 | 0.80 | NR1I2 (0.38) | NR1I2CYP3A4CYP2D6PPARA | |
| SCHEMBL9209889 | 0.78 | PPARA (0.44) | NR1I2CYP3A4CYP2D6PPARA | |
| SCHEMBL9206575 | 0.77 | PPARA (0.41) | NR1I2CYP3A4CYP2D6PPARA | |
| SCHEMBL5089005 | 0.77 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6PPARA | |
| SCHEMBL9207573 | 0.76 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | disclosed |