Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215610 | 0.92 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9AMCHR1 | |
| SCHEMBL9212953 | 0.89 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AMCHR1 | |
| Hydrochloric Acid SCHEMBL9207896 | 0.89 | MEN1 (0.42) | MEN1KMT2ANPC1RAB9AMCHR1 | |
| Hydrochloric Acid SCHEMBL9215351 | 0.84 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AMCHR1 | |
| Hydrochloric Acid SCHEMBL9213083 | 0.82 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL9216849 | 0.81 | HRH3 (0.42) | MCHR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL9206975 | 0.80 | ALDH1A1 (0.35) | GAA | |
| SCHEMBL9208026 | 0.80 | HTR1A (0.43) | MEN1KMT2AMCHR1HTR1ASLC6A4 | |
| SCHEMBL9208130 | 0.80 | HRH3 (0.44) | MCHR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL9216007 | 0.80 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |