Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350297 | 0.80 | ENPP2 (0.56) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL24261209 | 0.79 | ENPP2 (0.55) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL16167023 | 0.79 | ENPP2 (0.55) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL299759 | 0.78 | OPRM1 (0.56) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL30001086 | 0.78 | OPRM1 (0.56) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL3506161 | 0.78 | ENPP2 (0.54) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL28879888 | 0.78 | ENPP2 (0.54) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL20534706 | 0.77 | ENPP2 (0.52) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL7651106 | 0.77 | ENPP2 (0.52) | ENPP2DRD2DRD1TAAR1CYP3A4 | |
| SCHEMBL25620321 | 0.77 | ENPP2 (0.52) | ENPP2DRD2DRD1TAAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | claimed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | claimed |
| JP-1230568-A | — | — | None | — | — | JP | disclosed |
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0317292-B1 | NEW ANTIBIOTICS OF THE MUREIDOMYCIN GROUP, THEIR PREPARATION, AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| JP-H01230568-A | MUREIDOMYCIN DERIVATIVE | SANKYO CO LTD | 1989-09-14 | — | — | JP | disclosed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | disclosed |