Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213695 | 0.85 | L3MBTL1 (0.46) | CNR1CNR2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL9219551 | 0.85 | L3MBTL1 (0.46) | CNR1CNR2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL9218058 | 0.84 | L3MBTL1 (0.44) | CNR1CNR2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL9212636 | 0.82 | TP53 (0.49) | CNR1CNR2L3MBTL1ALDH1A1TP53 | |
| SCHEMBL9219857 | 0.81 | NAAA (0.48) | CNR1CNR2ALDH1A1HPGDKDM4E | |
| SCHEMBL9212406 | 0.78 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1HPGDTP53LMNA | |
| SCHEMBL9209891 | 0.78 | HPGD (0.45) | CNR1CNR2ALDH1A1HPGDKDM4E | |
| SCHEMBL9219621 | 0.78 | CSNK2A2 (0.46) | ALDH1A1HPGDKDM4ETP53LMNA | |
| SCHEMBL9219544 | 0.76 | TP53 (0.50) | CNR1CNR2L3MBTL1TP53MDM2 | |
| SCHEMBL9430499 | 0.76 | TP53 (0.50) | CNR1CNR2L3MBTL1TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |