Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9217805 | 0.99 | MEN1 (0.51) | MEN1KMT2AOPRM1SIGMAR1ACHE | |
| SCHEMBL27618798 | 0.86 | SIGMAR1 (0.51) | MEN1KMT2AOPRM1SIGMAR1ACHE | |
| SCHEMBL6749692 | 0.84 | OPRM1 (0.54) | OPRM1SIGMAR1ACHEABL1RIN1 | |
| Hydrochloric Acid SCHEMBL7684853 | 0.81 | OPRM1 (0.50) | OPRM1SIGMAR1ACHEABL1RIN1 | |
| SCHEMBL6745787 | 0.78 | CHRM3 (0.56) | OPRM1ACHECHRM3BCHE | |
| SCHEMBL29072067 | 0.77 | SMN1; SMN2 (0.46) | MEN1KMT2A | |
| SCHEMBL18458295 | 0.75 | SIGMAR1 (0.56) | MEN1KMT2AOPRM1SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7107750 | 0.75 | ABL1 (0.51) | OPRM1SIGMAR1ACHEABL1RIN1 | |
| SCHEMBL9220507 | 0.75 | MEN1 (0.55) | MEN1KMT2AOPRM1SIGMAR1ACHE | |
| SCHEMBL27053340 | 0.74 | MEN1 (0.41) | MEN1KMT2ACHRM3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320032-B1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1995-01-18 | — | — | EP | disclosed |
| US-5231184-A | Viricide intermediate | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-27 | — | — | US | disclosed |
| US-5106973-A | Viricide intermediates | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-21 | — | — | US | disclosed |
| US-4992433-A | Viricides | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-12 | — | — | US | disclosed |
| EP-0320032-A1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-06-14 | — | — | EP | disclosed |