Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9649933 | 0.83 | TSPO (0.53) | GAAPOLB | |
| SCHEMBL9649405 | 0.83 | KDM4E (0.50) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL11090098 | 0.79 | ADORA3 (0.55) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL10730143 | 0.75 | KDM4E (0.50) | ALDH1A1KMT2AMEN1GAAKDM4E | |
| SCHEMBL2214591 | 0.74 | GAA (0.50) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL2214750 | 0.73 | CNR2 (0.71) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL9649918 | 0.72 | CYP1A2 (0.56) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL8817316 | 0.72 | ADORA3 (0.42) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL9650033 | 0.72 | ADORA3 (0.58) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL17625298 | 0.72 | F10 (0.58) | ALDH1A1LMNAKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446141-B1 | Imidazo[1,2-c]quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-01-18 | — | — | EP | claimed |
| US-5128338-A | Cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1992-07-07 | — | — | US | claimed |
| JP-4217682-A | — | — | None | — | — | JP | disclosed |
| JP-H04217682-A | IMIDAZO(1,2-C)QUINAZOLINE DERIVATIVE, PREPARATION THEREOF, AND DRUG OF ANGINAPECTORIS INCLUDING THE SAME | ADIR | 1992-08-07 | — | — | JP | disclosed |
| US-5128338-A | Cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1992-07-07 | — | — | US | disclosed |