Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 7/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 7/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213275 | 1.00 | PNMT (0.38) | PNMTKCNA5CNR2KDM1AKCNE1 | |
| SCHEMBL9213253 | 1.00 | PNMT (0.38) | PNMTKCNA5CNR2KDM1AKCNE1 | |
| SCHEMBL9270605 | 0.84 | PNMT (0.39) | PNMTKCNA5CNR2KCNE1KCNQ1 | |
| SCHEMBL9270610 | 0.84 | PNMT (0.39) | PNMTKCNA5CNR2KCNE1KCNQ1 | |
| SCHEMBL9753173 | 0.84 | IDO1 (0.36) | KCNA5CNR2KCNE1KCNQ1BACE1 | |
| SCHEMBL9753172 | 0.84 | IDO1 (0.36) | KCNA5CNR2KCNE1KCNQ1BACE1 | |
| SCHEMBL9753169 | 0.84 | IDO1 (0.36) | KCNA5CNR2KCNE1KCNQ1BACE1 | |
| SCHEMBL9270612 | 0.84 | PNMT (0.39) | PNMTKCNA5CNR2KCNE1KCNQ1 | |
| SCHEMBL9221034 | 0.78 | KCNE1 (0.51) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL9221043 | 0.78 | KCNE1 (0.51) | KCNE1KCNQ1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | claimed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | disclosed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |