Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ADH1B | P00325 | 2/20 | 0.35 |
| ▸ | ADH1C | P00326 | 2/20 | 0.35 |
| ▸ | ADH1A | P07327 | 2/20 | 0.35 |
| ▸ | ADH4 | P08319 | 2/20 | 0.35 |
| ▸ | ADH7 | P40394 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23995930 | 0.84 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL15418241 | 0.83 | MMP8 (0.43) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL19205925 | 0.82 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL21808586 | 0.82 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL7770667 | 0.82 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL25122655 | 0.82 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL20317563 | 0.82 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL24508589 | 0.82 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL7775120 | 0.82 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL19963745 | 0.82 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |