Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212147 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMETAP2CYP1A2PLA2G1B | |
| SCHEMBL9214590 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMETAP2CYP1A2PLA2G1B | |
| SCHEMBL24684546 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KMT2AMETAP2CYP1A2PLA2G1B | |
| SCHEMBL9205702 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KMT2AMETAP2CYP1A2PLA2G1B | |
| SCHEMBL9209780 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KMT2AMETAP2CYP1A2PLA2G1B | |
| SCHEMBL9210264 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KMT2AMETAP2CYP1A2PLA2G1B | |
| SCHEMBL8229893 | 0.92 | CYP1A2 (0.48) | ALDH1A1KMT2AMETAP2CYP1A2REN | |
| SCHEMBL5072427 | 0.92 | CYP1A2 (0.48) | ALDH1A1KMT2AMETAP2CYP1A2REN | |
| SCHEMBL20830414 | 0.88 | OPRM1 (0.44) | ALDH1A1KMT2AMETAP2PLA2G1BPLA2G2A | |
| SCHEMBL13242434 | 0.84 | CYP1A2 (0.41) | ALDH1A1KMT2AMETAP2CYP1A2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |