Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 6/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366043 | 0.79 | — | — | |
| SCHEMBL15879474 | 0.79 | — | — | |
| SCHEMBL5711100 | 0.79 | — | — | |
| SCHEMBL9550079 | 0.79 | LMNA (0.65) | LMNAMAOASLC6A2PKMALDH1A1 | |
| SCHEMBL2288476 | 0.78 | LMNA (0.49) | LMNAMAOASLC6A2PKMALDH1A1 | |
| SCHEMBL20519513 | 0.78 | LMNA (0.49) | LMNAMAOASLC6A2PKMALDH1A1 | |
| SCHEMBL21428625 | 0.78 | LMNA (0.49) | LMNAMAOASLC6A2PKMALDH1A1 | |
| SCHEMBL18457351 | 0.77 | LMNA (0.48) | LMNAMAOASLC6A2PKMALDH1A1 | |
| SCHEMBL19341995 | 0.76 | LMNA (0.58) | LMNAMAOASLC6A2PKMALDH1A1 | |
| SCHEMBL19341993 | 0.76 | LMNA (0.58) | LMNAMAOASLC6A2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |