Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214125 | 0.90 | KIT (0.42) | UCHL1KITKMT2AMAPTALDH1A1 | |
| SCHEMBL9174951 | 0.89 | KIT (0.46) | KITKMT2AMAPTLMNAPTPN2 | |
| SCHEMBL9167954 | 0.88 | PKM (0.50) | UCHL1KITKMT2AMAPTTP53 | |
| SCHEMBL9220912 | 0.88 | UQCRB (0.49) | UCHL1KITMAPTLMNAPTPN2 | |
| SCHEMBL9219528 | 0.86 | CES1 (0.48) | KITKMT2AMAPTPTPN2PTPN1 | |
| SCHEMBL9169588 | 0.86 | UQCRB (0.46) | KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL9216550 | 0.86 | MAPT (0.49) | KMT2AMAPTTP53PTPN2PTPN1 | |
| SCHEMBL9173978 | 0.86 | UQCRB (0.52) | KMT2AMAPTLMNAPTPN5ALDH1A1 | |
| SCHEMBL9163477 | 0.86 | KIT (0.48) | KITMAPTLMNAALDH1A1GHSR | |
| SCHEMBL9218723 | 0.86 | MAPT (0.49) | KMT2AL3MBTL1MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269859-B2 | Pyrazolotriazine compounds | OTSUKA PHARMA CO LTD (JP) | 1995-10-18 | — | — | EP | disclosed |
| EP-0503099-A1 | PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |