Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.48 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17981373 | 0.92 | CA2 (0.52) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL20546267 | 0.92 | CA2 (0.52) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL27564186 | 0.88 | CA2 (0.75) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL5508045 | 0.86 | CA2 (0.61) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL15905507 | 0.86 | CA2 (0.61) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL27517270 | 0.86 | MEN1 (0.55) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL17981439 | 0.83 | MEN1 (0.49) | CA2CA1FOLH1MEN1KMT2A | |
| SCHEMBL20546624 | 0.83 | MEN1 (0.49) | CA2CA1FOLH1MEN1KMT2A | |
| Water SCHEMBL11503927 | 0.82 | CA2 (0.64) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL715646 | 0.82 | CA2 (0.67) | CA2CA1FOLH1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995009845-A1 | PYRIMIDINYL-GLUTAMIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1995-04-13 | — | — | WO | disclosed |