Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217125 | 0.92 | ACHE (0.46) | ACHEHRH3KDM4E | |
| SCHEMBL9218017 | 0.91 | ACHE (0.47) | ACHEALDH1A1HRH3CYP3A4KDM4E | |
| SCHEMBL9218033 | 0.91 | ACHE (0.47) | ACHEALDH1A1HRH3CYP3A4KDM4E | |
| SCHEMBL9212797 | 0.89 | ACHE (0.38) | ACHE | |
| SCHEMBL9208005 | 0.88 | ACHE (0.37) | ACHEHRH3 | |
| SCHEMBL9217083 | 0.87 | ACHE (0.36) | ACHEALDH1A1HRH3KDM4E | |
| SCHEMBL9210553 | 0.85 | ACHE (0.37) | ACHEALDH1A1POLB | |
| SCHEMBL9219515 | 0.84 | SCN9A (0.32) | ACHEHRH3 | |
| Fumaric Acid SCHEMBL29754133 | 0.84 | ACHE (0.44) | ACHEHRH3KDM4E | |
| SCHEMBL9276600 | 0.83 | ACHE (0.37) | ACHEHTTALDH1A1POLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413343-B1 | Furan derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |