Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218017 | 1.00 | ACHE (0.47) | ACHEKDM4EGAAHRH3DPP7 | |
| SCHEMBL9217125 | 0.99 | ACHE (0.46) | ACHEKDM4EGAAHRH3DPP7 | |
| Fumaric Acid SCHEMBL29754133 | 0.93 | ACHE (0.44) | ACHEKDM4EGAAHRH3 | |
| SCHEMBL9213773 | 0.91 | ACHE (0.38) | ACHEKDM4EHRH3ALDH1A1CYP3A4 | |
| SCHEMBL9212797 | 0.90 | ACHE (0.38) | ACHE | |
| SCHEMBL9208005 | 0.89 | ACHE (0.37) | ACHEHRH3 | |
| SCHEMBL9217083 | 0.88 | ACHE (0.36) | ACHEKDM4EHRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9276600 | 0.88 | ACHE (0.37) | ACHEKDM4EHRH3ALDH1A1HPGD | |
| SCHEMBL9273208 | 0.87 | ACHE (0.36) | ACHEKDM4EGAAHRH3ALDH1A1 | |
| SCHEMBL9210553 | 0.86 | ACHE (0.37) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413343-B1 | Furan derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |