Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.35 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414183 | 0.81 | ALDH1A1 (0.63) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL9213893 | 0.80 | ALDH1A1 (0.51) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL6907412 | 0.78 | ALDH1A1 (0.51) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL10536548 | 0.78 | ALDH1A1 (0.84) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL9211212 | 0.78 | ALDH1A1 (0.51) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL9213147 | 0.78 | ALDH1A1 (0.54) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL9723347 | 0.77 | ALDH1A1 (0.51) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL9212491 | 0.76 | NR1I2 (0.76) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL9633714 | 0.76 | ALDH1A1 (0.50) | TP53ALDH1A1TDP1CYP3A4NR1I2 | |
| SCHEMBL9210761 | 0.75 | ALDH1A1 (0.59) | TP53ALDH1A1TDP1CYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108482-A | Protect crep plant against phytotoxic action of herbicide; plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-04-28 | — | — | US | claimed |
| EP-0397602-A1 | N-phenylpyrrolidines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | claimed |
| EP-0378508-B1 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| US-5175289-A | Antidotes for protecting cultivated plants from the phytotoxic action of herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5108482-A | Protect crep plant against phytotoxic action of herbicide; plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| US-5041157-A | Protecting soybeans or cereals | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0397602-A1 | N-phenylpyrrolidines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | disclosed |
| EP-0378508-A2 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA-GEIGY AG (CH) | 1990-07-18 | — | — | EP | disclosed |