Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GPX4 | P36969 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634306 | 0.84 | THRB (0.48) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL9633714 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL9213896 | 0.77 | TP53 (0.55) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL11569945 | 0.77 | TP53 (0.54) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL10414183 | 0.75 | ALDH1A1 (0.63) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL4659790 | 0.73 | RORC (0.56) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL7274378 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL10970495 | 0.73 | RORC (0.56) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL6880404 | 0.72 | THRB (0.67) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL6880410 | 0.72 | THRB (0.67) | ALDH1A1TP53TDP1CYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108482-A | Protect crep plant against phytotoxic action of herbicide; plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-04-28 | — | — | US | claimed |
| US-5175289-A | Antidotes for protecting cultivated plants from the phytotoxic action of herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5108482-A | Protect crep plant against phytotoxic action of herbicide; plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| US-5041157-A | Protecting soybeans or cereals | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |