Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FCER2 | P06734 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484144 | 1.00 | NOD1 (0.46) | NOD1DPP4ERAP2ERAP1LNPEP | |
| SCHEMBL18862286 | 1.00 | NOD1 (0.46) | NOD1DPP4ERAP2ERAP1LNPEP | |
| SCHEMBL14298799 | 0.88 | ALDH1A1 (0.47) | NOD1DPP4MMP2MMP9MMP8 | |
| SCHEMBL27579877 | 0.87 | DPP4 (0.40) | NOD1DPP4ERAP2ERAP1LNPEP | |
| SCHEMBL27579872 | 0.87 | DPP4 (0.40) | NOD1DPP4ERAP2ERAP1LNPEP | |
| SCHEMBL10363299 | 0.86 | SLC7A5 (0.47) | ERAP2ERAP1LNPEPMMP2MMP9 | |
| SCHEMBL10363301 | 0.86 | SLC7A5 (0.47) | ERAP2ERAP1LNPEPMMP2MMP9 | |
| SCHEMBL22623434 | 0.86 | ALDH1A1 (0.44) | ERAP2ERAP1LNPEPMMP2MMP9 | |
| SCHEMBL14268997 | 0.86 | ALDH1A1 (0.44) | ERAP2ERAP1LNPEPMMP2MMP9 | |
| SCHEMBL24915226 | 0.86 | ALDH1A1 (0.44) | ERAP2ERAP1LNPEPMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240167070-A1 | METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-05-23 | — | — | US | disclosed |
| US-10851367-B2 | Tissue-specific genome engineering using CRISPR-Cas9 | PFIZER INC. (US) | 2020-12-01 | — | — | US | disclosed |
| EP-0295316-B1 | Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones | AMERICAN CYANAMID CO (US) | 1995-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240167070-A1 | METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE | ANPEP, DNPEP, ASNS | NOD1 213/4885DPP4 545/4885ERAP2 653/4885 |
| US-10851367-B2 | Tissue-specific genome engineering using CRISPR-Cas9 | ASGR1, LDLR, HAVCR2 | NOD1 2140/4885DPP4 2149/4885ERAP2 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.