Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.43 |
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | DRD1 | P21728 | 6/20 | 0.41 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
| ▸ | DRD5 | P21918 | 6/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781532 | 1.00 | DRD3 (0.43) | DRD3DRD2OPRM1OPRD1OPRK1 | |
| SCHEMBL9214632 | 1.00 | DRD3 (0.43) | DRD3DRD2OPRM1OPRD1OPRK1 | |
| SCHEMBL4476492 | 0.90 | MC4R (0.44) | DRD3DRD2OPRM1OPRK1ALDH1A1 | |
| SCHEMBL9616766 | 0.89 | ALDH1A1 (0.46) | DRD3DRD2OPRM1OPRD1OPRK1 | |
| SCHEMBL4493879 | 0.84 | BCHE (0.40) | DRD3DRD2OPRM1OPRK1ALDH1A1 | |
| SCHEMBL9781490 | 0.83 | CNR2 (0.43) | ALDH1A1CYP3A4MC4RTHRATHRB | |
| SCHEMBL7070859 | 0.83 | ALDH1A1 (0.53) | OPRM1OPRD1OPRK1ALDH1A1CYP3A4 | |
| SCHEMBL7532689 | 0.83 | MC4R (0.53) | DRD3DRD2OPRM1OPRK1ALDH1A1 | |
| SCHEMBL14288494 | 0.83 | MC4R (0.53) | DRD3DRD2OPRM1OPRK1ALDH1A1 | |
| SCHEMBL11474722 | 0.83 | ALDH1A1 (0.38) | OPRM1OPRD1OPRK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380677-B1 | FLUORAN COMPOUNDS AND COLOR-FORMING RECORDING MATERIALS CONTAINING SAME | NIPPON SODA CO (JP) | 1995-11-22 | — | — | EP | disclosed |
| US-5017710-A | Solubility, storage stability | NIPPON SODA CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0380677-A1 | FLUORAN COMPOUNDS AND COLOR-FORMING RECORDING MATERIALS CONTAINING SAME | NIPPON SODA CO., LTD. (JP) | 1990-08-08 | — | — | EP | disclosed |