Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208004 | 0.98 | CYP19A1 (0.38) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9205209 | 0.88 | CHRM1 (0.35) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL23920955 | 0.79 | ACHE (0.35) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL22268975 | 0.79 | ACHE (0.35) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL11421607 | 0.68 | ACHE (0.36) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL6751772 | 0.67 | TSHR (0.42) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL6752031 | 0.67 | TSHR (0.42) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL1754051 | 0.67 | TSHR (0.42) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL6748375 | 0.67 | TSHR (0.42) | LIPGCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL1753858 | 0.67 | TSHR (0.42) | LIPGCHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |