Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214886 | 1.00 | HSD17B7 (0.58) | HSD17B7 | |
| SCHEMBL13656755 | 0.89 | SHBG (0.62) | HSD17B7 | |
| SCHEMBL4268268 | 0.89 | SHBG (0.62) | HSD17B7 | |
| SCHEMBL4268271 | 0.89 | SHBG (0.62) | HSD17B7 | |
| SCHEMBL8077567 | 0.85 | HSD17B7 (0.54) | HSD17B7 | |
| SCHEMBL4265828 | 0.84 | HSD17B7 (0.64) | HSD17B7 | |
| SCHEMBL13656756 | 0.84 | HSD17B7 (0.64) | HSD17B7 | |
| SCHEMBL4265826 | 0.84 | HSD17B7 (0.64) | HSD17B7 | |
| SCHEMBL6692574 | 0.84 | HSD17B7 (0.53) | HSD17B7 | |
| SCHEMBL5069378 | 0.82 | HSD17B7 (0.61) | HSD17B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468012-B1 | 17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1995-09-20 | — | — | EP | disclosed |
| US-5155107-A | Inhibiting androgen action, anticarcinogenic agents, treating skin disorders, baldness | FARMITALIA CARLO ERBA (IT) | 1992-10-13 | — | — | US | disclosed |
| EP-0468012-A1 | 17-g(b)-SUBSTITUTED-4-AZA-5-g(a)-ANDROSTAN-3-ONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1992-01-29 | — | — | EP | disclosed |
| WO-1991012261-A1 | 17β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-08-22 | — | — | WO | disclosed |