Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948931 | 0.92 | MRGPRX4 (0.42) | HIF1AMRGPRX4FFAR1MAOBRAB9A | |
| SCHEMBL8948927 | 0.92 | MRGPRX4 (0.42) | HIF1AMRGPRX4FFAR1MAOBRAB9A | |
| SCHEMBL9223392 | 0.78 | MEN1 (0.44) | HIF1AFFAR1SMN1; SMN2RXFP1 | |
| SCHEMBL8948955 | 0.78 | MTNR1A (0.40) | MTNR1A | |
| SCHEMBL8948952 | 0.78 | MTNR1A (0.40) | MTNR1A | |
| SCHEMBL8948942 | 0.77 | MRGPRX4 (0.43) | MRGPRX4FFAR1MAOBRAB9ANPC1 | |
| SCHEMBL8948936 | 0.77 | MRGPRX4 (0.43) | MRGPRX4FFAR1MAOBRAB9ANPC1 | |
| SCHEMBL8948946 | 0.77 | MRGPRX4 (0.43) | MRGPRX4FFAR1MAOBRAB9ANPC1 | |
| SCHEMBL9222166 | 0.76 | MRGPRX4 (0.42) | MRGPRX4FFAR1MAOBRAB9ANPC1 | |
| SCHEMBL9213563 | 0.76 | MRGPRX4 (0.42) | MRGPRX4FFAR1MAOBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525516-B1 | Derivatives of beta substituted cinnomic acid | BASF AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0525516-A2 | Derivatives of beta substituted cinnomic acid | BASF Aktiengesellschaft (DE) | 1993-02-03 | — | — | EP | disclosed |