Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222166 | 1.00 | MRGPRX4 (0.42) | MRGPRX4RAB9AFFAR1MAOBTP53 | |
| SCHEMBL8948942 | 0.92 | MRGPRX4 (0.43) | MRGPRX4RAB9AFFAR1MAOBTP53 | |
| SCHEMBL8948936 | 0.92 | MRGPRX4 (0.43) | MRGPRX4RAB9AFFAR1MAOBTP53 | |
| SCHEMBL8948946 | 0.92 | MRGPRX4 (0.43) | MRGPRX4RAB9AFFAR1MAOBTP53 | |
| SCHEMBL9214778 | 0.80 | NR4A2 (0.44) | SMN1; SMN2 | |
| SCHEMBL9218125 | 0.78 | MTNR1A (0.44) | RAB9ANPC1 | |
| SCHEMBL8948927 | 0.77 | MRGPRX4 (0.42) | MRGPRX4RAB9AFFAR1MAOBTP53 | |
| SCHEMBL8948931 | 0.77 | MRGPRX4 (0.42) | MRGPRX4RAB9AFFAR1MAOBTP53 | |
| SCHEMBL9213636 | 0.77 | MTNR1A (0.43) | RAB9ARXFP1NPC1 | |
| SCHEMBL9222769 | 0.77 | MTNR1A (0.43) | RAB9ARXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525516-B1 | Derivatives of beta substituted cinnomic acid | BASF AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0525516-A2 | Derivatives of beta substituted cinnomic acid | BASF Aktiengesellschaft (DE) | 1993-02-03 | — | — | EP | disclosed |