Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.66 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215301 | 1.00 | AHCY (0.66) | AHCYHSPA8HSPA5PDE4APDE4B | |
| SCHEMBL9223113 | 0.88 | AHCY (0.64) | AHCYHSPA8HSPA5PDE4APDE4B | |
| SCHEMBL9223106 | 0.88 | AHCY (0.64) | AHCYHSPA8HSPA5PDE4APDE4B | |
| SCHEMBL9216846 | 0.80 | AHCY (1.00) | AHCYSLC28A2GAPDH | |
| SCHEMBL9214858 | 0.80 | AHCY (1.00) | AHCYSLC28A2GAPDH | |
| SCHEMBL9214869 | 0.80 | AHCY (1.00) | AHCYSLC28A2GAPDH | |
| SCHEMBL9213150 | 0.75 | AHCY (0.58) | AHCYHSPA8HSPA5PDE4APDE4B | |
| SCHEMBL864060 | 0.75 | AHCY (0.58) | AHCYHSPA8HSPA5PDE4APDE4B | |
| SCHEMBL9217733 | 0.73 | AHCY (0.60) | AHCYHSPA8HSPA5PDE4APDE4B | |
| SCHEMBL9217727 | 0.73 | AHCY (0.60) | AHCYHSPA8HSPA5PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347852-B1 | Novel neplanocin derivatives | MERRELL DOW PHARMA (US) | 1995-08-23 | — | — | EP | claimed |
| EP-0347852-A2 | Novel neplanocin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-27 | — | — | EP | claimed |
| EP-0347852-B1 | Novel neplanocin derivatives | MERRELL DOW PHARMA (US) | 1995-08-23 | — | — | EP | disclosed |