Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 7/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | NADK | O95544 | 1/20 | 0.38 |
| ▸ | AMD1 | P17707 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217727 | 1.00 | AHCY (0.60) | AHCYPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL864060 | 0.87 | AHCY (0.58) | AHCYPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9213150 | 0.87 | AHCY (0.58) | AHCYPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9223106 | 0.76 | AHCY (0.64) | AHCYPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9223113 | 0.76 | AHCY (0.64) | AHCYPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9215378 | 0.75 | AHCY (1.00) | AHCYADORA2A | |
| SCHEMBL9215373 | 0.75 | AHCY (1.00) | AHCYADORA2A | |
| SCHEMBL9219751 | 0.75 | AHCY (1.00) | AHCYADORA2A | |
| SCHEMBL9215301 | 0.73 | AHCY (0.66) | AHCYPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9215307 | 0.73 | AHCY (0.66) | AHCYPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347852-B1 | Novel neplanocin derivatives | MERRELL DOW PHARMA (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0347852-A2 | Novel neplanocin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-27 | — | — | EP | disclosed |