SCHEMBL9215378

SCHEMBL9215378

Nc1ncnc2c1ncn2C1C(F)=CC(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHCY P23526 17/20 1.00
ADORA2A P29274 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215373 1.00 AHCY (1.00) AHCYADORA2A
SCHEMBL9219751 1.00 AHCY (1.00) AHCYADORA2A
SCHEMBL9214583 0.84 AHCY (0.72) AHCY
SCHEMBL9217782 0.84 AHCY (0.72) AHCY
SCHEMBL9214589 0.84 AHCY (0.72) AHCY
SCHEMBL9219837 0.81 AHCY (0.67) AHCYADORA2A
SCHEMBL9219846 0.81 AHCY (0.67) AHCYADORA2A
SCHEMBL9221842 0.81 AHCY (0.67) AHCYADORA2A
SCHEMBL9221846 0.81 AHCY (0.67) AHCYADORA2A
SCHEMBL9217733 0.75 AHCY (0.60) AHCYADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0347852-B1 Novel neplanocin derivatives MERRELL DOW PHARMA (US) 1995-08-23 EP claimed
EP-0347852-B1 Novel neplanocin derivatives MERRELL DOW PHARMA (US) 1995-08-23 EP disclosed
EP-0347852-A2 Novel neplanocin derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1989-12-27 EP disclosed