Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212929 | 0.90 | HRH3 (0.34) | HRH3 | |
| SCHEMBL9217125 | 0.86 | ACHE (0.46) | HRH3 | |
| SCHEMBL9217083 | 0.85 | ACHE (0.36) | HRH3ALDH1A1NPSR1 | |
| SCHEMBL9218017 | 0.85 | ACHE (0.47) | HRH3ALDH1A1 | |
| SCHEMBL9218033 | 0.85 | ACHE (0.47) | HRH3ALDH1A1 | |
| SCHEMBL9273208 | 0.84 | ACHE (0.36) | HRH3ALDH1A1 | |
| SCHEMBL9219515 | 0.82 | SCN9A (0.32) | HRH3 | |
| SCHEMBL9208005 | 0.82 | ACHE (0.37) | HRH3 | |
| SCHEMBL9210553 | 0.81 | ACHE (0.37) | ALDH1A1NPSR1 | |
| SCHEMBL9276600 | 0.81 | ACHE (0.37) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413343-B1 | Furan derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |