Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430879 | 0.90 | L3MBTL1 (0.42) | L3MBTL1PTPN1CLK4MAPTTP53 | |
| SCHEMBL9217698 | 0.88 | L3MBTL1 (0.40) | L3MBTL1MAOBPTPN1MAPTTP53 | |
| SCHEMBL9431302 | 0.88 | L3MBTL1 (0.49) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| Hydrochloric Acid SCHEMBL9213805 | 0.87 | L3MBTL1 (0.48) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| SCHEMBL9431173 | 0.87 | L3MBTL1 (0.43) | L3MBTL1PTPN1CLK4MAPTTP53 | |
| SCHEMBL9431764 | 0.86 | L3MBTL1 (0.43) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| Hydrochloric Acid SCHEMBL9216724 | 0.85 | L3MBTL1 (0.42) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| Hydrochloric Acid SCHEMBL9219672 | 0.83 | L3MBTL1 (0.39) | L3MBTL1MAOBPTPN1MAPTTP53 | |
| Hydrochloric Acid SCHEMBL9220707 | 0.83 | L3MBTL1 (0.43) | L3MBTL1PTPN1MAPTTP53ANO1 | |
| Hydrochloric Acid SCHEMBL9209347 | 0.83 | L3MBTL1 (0.48) | L3MBTL1PTPN1MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |