Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431173 | 0.97 | L3MBTL1 (0.43) | L3MBTL1PTPN1MAPTCXCR4TP53 | |
| SCHEMBL9431302 | 0.91 | L3MBTL1 (0.49) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| SCHEMBL9215410 | 0.90 | L3MBTL1 (0.40) | L3MBTL1PTPN1MAPTCXCR4TP53 | |
| Hydrochloric Acid SCHEMBL9213805 | 0.90 | L3MBTL1 (0.48) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| SCHEMBL9431764 | 0.89 | L3MBTL1 (0.43) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| Hydrochloric Acid SCHEMBL9216724 | 0.87 | L3MBTL1 (0.42) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| Hydrochloric Acid SCHEMBL9219672 | 0.86 | L3MBTL1 (0.39) | L3MBTL1PTPN1MAPTCXCR4TP53 | |
| Hydrochloric Acid SCHEMBL9220707 | 0.85 | L3MBTL1 (0.43) | L3MBTL1PTPN1MAPTTP53ANO1 | |
| SCHEMBL9217698 | 0.84 | L3MBTL1 (0.40) | L3MBTL1PTPN1MAPTTP53CSNK2A2 | |
| SCHEMBL9221219 | 0.83 | CA1 (0.43) | PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026738-A1 | N'-HETEROCYCLYL-N-BENZOFURANYL UREA DERIVATIVES AND THEIR ANALOGS AS ACAT INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |