Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523092 | 0.99 | EGFR (0.46) | EGFRRPS6KB1AKT1ESR1LMNA | |
| SCHEMBL8303141 | 0.86 | EGFR (0.38) | EGFRRPS6KB1AKT1LMNACRHR1 | |
| SCHEMBL9837138 | 0.85 | EGFR (0.47) | EGFRRPS6KB1AKT1ESR1LMNA | |
| SCHEMBL9869764 | 0.84 | CRHR1 (0.36) | EGFRCRHR1 | |
| SCHEMBL9524967 | 0.83 | CRHR1 (0.36) | EGFRCRHR1 | |
| SCHEMBL9523756 | 0.82 | CRHR1 (0.39) | EGFRRPS6KB1AKT1CRHR1 | |
| SCHEMBL9193841 | 0.82 | CRHR1 (0.39) | EGFRRPS6KB1AKT1MAPTCRHR1 | |
| SCHEMBL9526898 | 0.81 | RPS6KB1 (0.39) | EGFRRPS6KB1AKT1MAPT | |
| SCHEMBL9084666 | 0.81 | PTGER4 (0.40) | EGFRRPS6KB1CRHR1 | |
| SCHEMBL9216328 | 0.81 | AURKA (0.42) | EGFRRPS6KB1AKT1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3246281-A | — | — | None | — | — | JP | disclosed |
| EP-0370704-B1 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0264217-B1 | ARALKYLAMINOPYRIMIDINE DERIVATIVE, PROCESS FOR PRODUCING THEREOF AND INSECTICIDE, ACARICIDE AND FUNGICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | UBE INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-5141941-A | ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| JP-H03246281-A | ARALKYLAMINE DERIVATIVE, ITS PRODUCTION AND FUNGICIDE | UBE IND LTD | 1991-11-01 | — | — | JP | disclosed |
| EP-0432894-A1 | Fungicidal composition | UBE INDUSTRIES, LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |
| EP-0424125-A2 | Aralkylamine derivatives, preparation method thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4985426-A | AGRICULTURAL USE | UBE INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0370704-A2 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4895849-A | Aralkylaminopyrimidine compounds which are useful as for producing thereof and insecticides | UBE INDUSTRIES, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0264217-A2 | Aralkylaminopyrimidine derivative, process for producing thereof and insecticide, acaricide and fungicide containing said derivative as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1988-04-20 | — | — | EP | disclosed |