Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282132 | 0.89 | AKT1 (0.44) | EGFRRPS6KB1LMNAAKT1P2RX3 | |
| SCHEMBL11289908 | 0.89 | LMNA (0.41) | EGFRRPS6KB1LMNAAKT1P2RX3 | |
| SCHEMBL11281906 | 0.86 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3 | |
| SCHEMBL9215503 | 0.85 | EGFR (0.47) | EGFRRPS6KB1LMNAAKT1ESR1 | |
| SCHEMBL9523092 | 0.84 | EGFR (0.46) | EGFRRPS6KB1LMNAAKT1ESR1 | |
| SCHEMBL23037 | 0.81 | CRHR1 (0.38) | EGFRRPS6KB1LMNAMAPT | |
| SCHEMBL9729031 | 0.78 | EGFR (0.36) | EGFRRPS6KB1LMNAAKT1 | |
| SCHEMBL9821894 | 0.77 | CXCR2 (0.38) | EGFRRPS6KB1LMNAAKT1 | |
| SCHEMBL8024790 | 0.74 | LMNA (0.38) | EGFRRPS6KB1LMNAAKT1P2RX3 | |
| SCHEMBL15684928 | 0.73 | LMNA (0.43) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424125-A2 | Aralkylamine derivatives, preparation method thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |