SCHEMBL9215514

SCHEMBL9215514

Cc1cc(O)c2c(c1)C(C)(C)CCC2(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
TP53 P04637 1/20 0.46
HNF4A P41235 3/20 0.41
SELL P14151 1/20 0.39
SELP P16109 1/20 0.39
SELE P16581 1/20 0.39
ACHE P22303 1/20 0.39
RXRA P19793 5/20 0.36
RARB P10826 4/20 0.36
RARA P10276 4/20 0.36
RXRB P28702 2/20 0.36
RXRG P48443 2/20 0.36
RARG P13631 2/20 0.36
TSHR P16473 2/20 0.34
GLA P06280 1/20 0.34
ALOX12 P18054 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TNNI3 P19429 1/20 0.33
TNNT2 P45379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11157848 0.84 ACHE (0.40) CYP1A2TP53SELLSELPSELE
SCHEMBL3692773 0.82 CYP1A2 (0.47) CYP1A2TP53HNF4ARXRARARB
SCHEMBL9077794 0.79 HNF4A (0.40) CYP1A2TP53HNF4ARXRARARB
SCHEMBL3063968 0.78 CYP1A2 (0.44) CYP1A2TP53HNF4ARXRARARB
SCHEMBL12809929 0.78 CYP1A2 (0.44) CYP1A2TP53HNF4ARXRARARB
SCHEMBL21565109 0.78 ACHE (0.38) CYP1A2TP53SELLSELPSELE
SCHEMBL24701548 0.76 HNF4A (0.35) CYP1A2TP53HNF4ARXRARARB
SCHEMBL27033882 0.76 HNF4A (0.35) CYP1A2TP53HNF4ARXRARARB
SCHEMBL9217030 0.76 TP53 (0.46) CYP1A2TP53HNF4ARXRARARB
SCHEMBL3689458 0.76 CYP3A4 (0.44) CYP1A2TP53HNF4ARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995000114-A1 TETRALINE® FORMATE ESTER AROMA CHEMICALS UNION CAMP CORPORATION (US) 1995-01-05 WO disclosed
US-5292719-A Perfumes, colognes, soaps and cosmetics; musk aroma UNION CAMP CORPORATION (US) 1994-03-08 US disclosed
US-4605778-A METHYLATION, FORMYLATION FRITZSCHE DODGE & OLCOTT INC. (US) 1986-08-12 US disclosed
EP-0098546-B1 NOVEL AROMATIC MUSKS FRITZSCHE DODGE & OLCOTT INC. (US) 1985-06-05 EP disclosed
US-4483786-A PERFUMES0 FRITZSCHE DODGE & OLCOTT INC. (US) 1984-11-20 US disclosed
US-4476040-A TETRAHYDRONAPMTHALENEALDEMYDE ALCOHOLS OR ETHERS FRITZSCHE, DODGE & OLCOTT, INC. (US) 1984-10-09 US disclosed
EP-0098546-A1 Novel aromatic musks FRITZSCHE DODGE & OLCOTT INC. (US) 1984-01-18 EP disclosed