Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215597 | 1.00 | SHBG (0.39) | SHBGMBOAT4MAPK1POLBAR | |
| SCHEMBL11036780 | 0.87 | STS (0.44) | SHBGMBOAT4MAPK1POLBAR | |
| SCHEMBL11336320 | 0.87 | STS (0.44) | SHBGMBOAT4MAPK1POLBAR | |
| SCHEMBL11036779 | 0.87 | STS (0.44) | SHBGMBOAT4MAPK1POLBAR | |
| SCHEMBL13855720 | 0.82 | SHBG (0.55) | SHBGMAPK1POLBARLMNA | |
| SCHEMBL4115261 | 0.82 | SHBG (0.55) | SHBGMAPK1POLBARLMNA | |
| SCHEMBL28827028 | 0.82 | SHBG (0.55) | SHBGMAPK1POLBARLMNA | |
| SCHEMBL4115264 | 0.82 | SHBG (0.55) | SHBGMAPK1POLBARLMNA | |
| SCHEMBL11332715 | 0.81 | SHBG (0.59) | SHBGMAPK1ARLMNAMAPT | |
| SCHEMBL11332711 | 0.81 | SHBG (0.59) | SHBGMAPK1ARLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438134-A | Endocrine disorders, reproductive control | JENAPHARM GMBH (DE) | 1995-08-01 | — | — | US | disclosed |
| WO-1992000991-A1 | PROCESS FOR PRODUCING UNSATURATED 17-ALPHA-CYANOMETHYL-17-BETA-HYDROXYSTEROIDS | JENAPHARM GMBH (DE) | 1992-01-23 | — | — | WO | disclosed |