Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212638 | 0.94 | ACHE (0.53) | ACHEBCHEADRA1B | |
| SCHEMBL9204663 | 0.86 | ACHE (0.52) | ACHEBCHEADRA1BMEN1KMT2A | |
| SCHEMBL9206874 | 0.86 | BCHE (0.42) | ACHEBCHEADRA1BMEN1KMT2A | |
| SCHEMBL9214063 | 0.86 | BCHE (0.44) | ACHEBCHEADRA1BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9740423 | 0.85 | CYP3A4 (0.42) | ACHEBCHEADRA1BMEN1KMT2A | |
| SCHEMBL9211577 | 0.82 | BCHE (0.46) | ACHEBCHEADRA1BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9207786 | 0.82 | DHCR7 (0.43) | MEN1KMT2A | |
| SCHEMBL9216056 | 0.81 | BCHE (0.44) | ACHEBCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9214816 | 0.80 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL9212375 | 0.80 | KDM4E (0.41) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |