Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204444 | 0.85 | KDM4E (0.43) | KDM4EBCHEACHECYP3A4CYP2D6 | |
| SCHEMBL9212638 | 0.85 | ACHE (0.53) | BCHEACHE | |
| SCHEMBL9215697 | 0.80 | ACHE (0.47) | BCHEACHE | |
| SCHEMBL9204663 | 0.78 | ACHE (0.52) | BCHEACHE | |
| SCHEMBL9212426 | 0.77 | PDE6D (0.39) | ACHE | |
| SCHEMBL9206993 | 0.75 | KCNH2 (0.38) | KDM4EBCHEACHECYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9213666 | 0.72 | PDE6D (0.37) | KCNH2 | |
| SCHEMBL9210290 | 0.72 | KCNH2 (0.41) | KDM4EBCHEACHECYP3A4CYP2D6 | |
| SCHEMBL9623765 | 0.71 | GNRHR (0.38) | KDM4EBCHECYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9208026 | 0.71 | HTR1A (0.43) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |