SCHEMBL9215751

SCHEMBL9215751

CCC(Cl)CC(=O)CC(Cl)CC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 3/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527420 0.89
SCHEMBL14040794 0.83 ALDH1A1 (0.31) TDP1ALDH1A1TSHRMAPK1
SCHEMBL6460666 0.80
SCHEMBL1131454 0.80
SCHEMBL4851976 0.80
SCHEMBL8424707 0.80
SCHEMBL7138128 0.78
SCHEMBL10623623 0.76 ALDH1A1 (0.40) TDP1ALDH1A1CYP2C9TSHR
SCHEMBL19714631 0.76 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL21811519 0.76 LMNA (0.44) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003239-B Bicyclic diterpenoid derivative, preparation method and application thereof 上海中医药大学 2024-05-17 CN disclosed
CN-117512599-B Preparation method and application of high-temperature-resistant and corrosion-inhibition water-soluble corrosion inhibitor 武汉三友石化有限公司 2024-04-12 CN disclosed
CN-117512599-A Preparation method and application of high-temperature-resistant and corrosion-inhibition water-soluble corrosion inhibitor 武汉三友石化有限公司 2024-02-06 CN disclosed
CN-116003239-A Bicyclic diterpenoid derivative, preparation method and application thereof 上海中医药大学 2023-04-25 CN disclosed
EP-0496012-B1 Process for the selective flotation of metal ores using 2-mercaptothiazole derivatives CONSIGLIO NAZIONALE RICERCHE (IT) 1995-07-19 EP disclosed
EP-0496012-A1 Process for the selective flotation of metal ores using 2-mercaptothiazole derivatives CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1992-07-29 EP disclosed
US-5120432-A Process for the selective flotation of metal ores using 2-mercaptothi-azole derivatives CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1992-06-09 US disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed