Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | SNCA | P37840 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RBP4 | P02753 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333849 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL9215847 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL26428237 | 0.95 | ALDH1A1 (0.46) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL26428189 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL7027547 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL5332333 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL9209368 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL9209366 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL8388735 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MAPTCYP3A4ALOX15APP | |
| SCHEMBL9749046 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4ALOX15APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454002-B1 | Dehydration process | HOFFMANN LA ROCHE (CH) | 1995-06-28 | — | — | EP | disclosed |
| US-5155255-A | PROCESS FOR PRODUCING CYCLOALKENYLALKENES | HOFFMANN-LA ROCHE INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0454002-A2 | Dehydration process | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-30 | — | — | EP | disclosed |