SCHEMBL9215892

SCHEMBL9215892

CC(C)=CCC/C(C)=C/COC(=O)CSc1nc2cccnc2s1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TRPV1 Q8NER1 3/20 0.46
PDK1 Q15118 1/20 0.40
ALOX15 P16050 1/20 0.40
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215911 1.00 ALDH1A1 (0.46) ALDH1A1TRPV1PDK1ALOX15HPGD
SCHEMBL9211585 0.83 ALDH1A1 (0.52) ALDH1A1PDK1HPGD
SCHEMBL9209204 0.77 ALDH1A1 (0.54) ALDH1A1PDK1HPGD
SCHEMBL9217714 0.76 ALDH1A1 (0.55) ALDH1A1PDK1HPGD
SCHEMBL9212949 0.75 PDK1 (0.58) ALDH1A1PDK1HPGD
SCHEMBL9214665 0.75 MAPT (0.63) ALDH1A1PDK1HPGD
SCHEMBL9217075 0.74 ALDH1A1 (0.51) ALDH1A1PDK1HPGD
SCHEMBL9215659 0.72 PDK1 (0.51) ALDH1A1PDK1HPGD
SCHEMBL9218853 0.71 ALDH1A1 (0.55) ALDH1A1PDK1ALOX15HPGD
SCHEMBL9215570 0.71 ALDH1A1 (0.54) ALDH1A1PDK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0405976-B1 Azole derivatives and antiulcerative composition containing same MEIJI SEIKA CO (JP) 1995-04-05 EP disclosed
US-5079255-A Nontoxic, acid stability MEIJI SEIKA KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
EP-0405976-A1 Azole derivatives and antiulcerative composition containing same MEIJI SEIKA KABUSHIKI KAISHA (JP) 1991-01-02 EP disclosed