Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002540 | 0.84 | SPR (0.71) | SPRCA1CA2CA7CA9 | |
| SCHEMBL15051627 | 0.83 | SPR (0.61) | SPRDRD2DRD1TAAR1CA1 | |
| SCHEMBL2749289 | 0.81 | SPR (0.63) | SPRDRD2DRD1TAAR1CA1 | |
| SCHEMBL4668612 | 0.81 | CA2 (0.63) | TAAR1CA1CA2CA7CA9 | |
| SCHEMBL12720969 | 0.80 | SPR (1.00) | SPRCA1CA2CA7CA9 | |
| SCHEMBL21776338 | 0.80 | SPR (0.66) | SPRTAAR1CA1CA2CA7 | |
| SCHEMBL19002545 | 0.80 | SPR (0.66) | SPRCA1CA2CA7CA9 | |
| SCHEMBL5632567 | 0.80 | SPR (0.66) | SPRDRD2DRD1TAAR1CA1 | |
| SCHEMBL17307601 | 0.80 | SPR (0.61) | SPRDRD2DRD1TAAR1CA1 | |
| SCHEMBL6976868 | 0.80 | CA1 (0.66) | TAAR1CA1CA2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | claimed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | claimed |
| JP-1230568-A | — | — | None | — | — | JP | disclosed |
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0317292-B1 | NEW ANTIBIOTICS OF THE MUREIDOMYCIN GROUP, THEIR PREPARATION, AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| JP-H01230568-A | MUREIDOMYCIN DERIVATIVE | SANKYO CO LTD | 1989-09-14 | — | — | JP | disclosed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | disclosed |