Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211431 | 0.96 | HRH3 (0.47) | HRH3MCHR1SLC6A4SIGMAR1MEN1 | |
| SCHEMBL9211025 | 0.88 | HRH3 (0.49) | HRH3SLC6A4SIGMAR1MEN1KMT2A | |
| SCHEMBL9207036 | 0.84 | HRH3 (0.50) | HRH3SLC6A4SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9216853 | 0.83 | DHCR7 (0.52) | SIGMAR1MEN1KMT2AABCB1ABCG2 | |
| SCHEMBL9213630 | 0.83 | ABCB1 (0.53) | HRH3ABCB1ABCG2 | |
| Hydrochloric Acid SCHEMBL9216849 | 0.83 | HRH3 (0.42) | HRH3MCHR1SLC6A4SIGMAR1LMNA | |
| SCHEMBL9214620 | 0.82 | ABCB1 (0.52) | HRH3ABCB1ABCG2 | |
| Hydrochloric Acid SCHEMBL9216030 | 0.81 | HRH3 (0.42) | HRH3SIGMAR1MEN1KMT2ACCR2 | |
| SCHEMBL9208130 | 0.81 | HRH3 (0.44) | HRH3MCHR1SLC6A4SIGMAR1 | |
| Bromide SCHEMBL9215762 | 0.80 | HRH3 (0.43) | HRH3MCHR1SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |