Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148377 | 0.89 | EPHA2 (0.57) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7849133 | 0.84 | EPHA2 (0.45) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7851217 | 0.84 | EPHA2 (0.45) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9218049 | 0.82 | LMNA (0.46) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9215553 | 0.82 | DPP4 (0.50) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9668533 | 0.81 | HPGD (0.41) | KMT2ALMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9668000 | 0.81 | LMNA (0.56) | KMT2ALMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9213820 | 0.79 | CYP3A4 (0.39) | KMT2ALMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9146420 | 0.79 | EPHA2 (0.71) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL6211209 | 0.78 | LMNA (0.37) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388298-B1 | Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines | ESTEVE LABOR DR (ES) | 1995-06-21 | — | — | EP | claimed |