Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668533 | 0.92 | HPGD (0.41) | PIM1ALDH1A1POLBLMNAMEN1 | |
| SCHEMBL9217114 | 0.90 | CYP3A4 (0.39) | CYP3A4CYP2C9ALDH1A1POLBCHRM2 | |
| SCHEMBL9150590 | 0.89 | CYP3A4 (0.50) | CYP3A4CYP2C9PIM1ALDH1A1POLB | |
| SCHEMBL9210485 | 0.83 | KDM4E (0.46) | CYP3A4CYP2C9ALDH1A1POLBCHRM2 | |
| SCHEMBL9215533 | 0.83 | ALDH1A1 (0.54) | CYP3A4CYP2C9ALDH1A1POLBCHRM2 | |
| SCHEMBL9667968 | 0.81 | EPHA2 (0.40) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL9048087 | 0.81 | KDM4E (0.41) | CYP3A4CYP2C9PIM1ALDH1A1POLB | |
| SCHEMBL9668000 | 0.80 | LMNA (0.56) | CYP2C9ALDH1A1POLBLMNAMEN1 | |
| SCHEMBL9216293 | 0.80 | CYP3A4 (0.40) | CYP3A4CYP2C9PIM1ALDH1A1POLB | |
| SCHEMBL9668529 | 0.80 | KDM4E (0.52) | PIM1ALDH1A1POLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388298-B1 | Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines | ESTEVE LABOR DR (ES) | 1995-06-21 | — | — | EP | claimed |