Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213857 | 0.93 | SCN3A (0.51) | SCN3A | |
| SCHEMBL9223074 | 0.85 | SCN3A (0.64) | SCN3A | |
| SCHEMBL9220961 | 0.82 | SCN3A (0.51) | SCN3A | |
| SCHEMBL9216059 | 0.81 | SCN3A (0.45) | SCN3A | |
| SCHEMBL9215988 | 0.81 | MAOB (0.46) | — | |
| SCHEMBL9215265 | 0.80 | LIPG (0.49) | — | |
| SCHEMBL9215229 | 0.80 | SCN3A (0.53) | SCN3A | |
| SCHEMBL9216479 | 0.77 | MAOB (0.54) | POLB | |
| SCHEMBL9217208 | 0.77 | MAOB (0.51) | SCN3A | |
| SCHEMBL9488175 | 0.76 | PPARD (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002575-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-26 | — | — | WO | claimed |
| WO-1995002575-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |