Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MMP15 | P51511 | 1/20 | 0.44 |
| ▸ | MMP16 | P51512 | 1/20 | 0.44 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492876 | 0.94 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL9215988 | 0.89 | MAOB (0.46) | MAOB | |
| SCHEMBL9215265 | 0.89 | LIPG (0.49) | FFAR1 | |
| SCHEMBL9597703 | 0.87 | SLC6A9 (0.46) | PPARD | |
| SCHEMBL9216295 | 0.86 | PPARD (0.49) | PPARDMAOB | |
| SCHEMBL9597206 | 0.85 | PPARD (0.43) | PPARD | |
| SCHEMBL9216059 | 0.85 | SCN3A (0.45) | MAOBFFAR1 | |
| SCHEMBL9492388 | 0.83 | MAOA (0.49) | MAOB | |
| SCHEMBL9488819 | 0.83 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL9216200 | 0.82 | PPARD (0.45) | PPARDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | claimed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | claimed |