SCHEMBL9216074

SCHEMBL9216074

Cc1cc2c(cc1C=O)C(C(C)C)C(C)C2(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32
GRIA4 P48058 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9119363 0.94 GRIA1 (0.32) GRIA1GRIA2GRIA3GRIA4
SCHEMBL9119138 0.87
SCHEMBL9153517 0.82
SCHEMBL23244036 0.79
SCHEMBL9209970 0.79
SCHEMBL5611209 0.77 GRIA1 (0.39) GRIA1GRIA2GRIA3GRIA4
SCHEMBL5396132 0.77 GRIA1 (0.39) GRIA1GRIA2GRIA3GRIA4
SCHEMBL29369649 0.77 GRIA1 (0.39) GRIA1GRIA2GRIA3GRIA4
SCHEMBL30292091 0.77 GRIA1 (0.39) GRIA1GRIA2GRIA3GRIA4
SCHEMBL30754351 0.77 GRIA1 (0.39) GRIA1GRIA2GRIA3GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090238785-A1 Novel Aldehydic Musks and Derivatives Thereof FLEXITRAL, INC. (US) 2009-09-24 US disclosed
US-20090238785-A1 Novel Aldehydic Musks and Derivatives Thereof FLEXITRAL, INC. (US) 2009-09-24 US disclosed
WO-2007111630-A1 COMPOUNDS WHICH RELEASE AN ODOR ON A CHANGE IN PH FLEXITRAL, INC. (US) 2007-10-04 WO disclosed
WO-2007102016-A1 USE OF A CYCLIC OR POLYCYCLIC MUSK BEARING AN ALDEHYDE GROUP FLEXITRAL, INC. (US) 2007-09-13 WO disclosed
WO-1995000113-A1 NOVEL FORMATE ESTER INDANE COMPOUNDS UNION CAMP CORPORATION (US) 1995-01-05 WO disclosed
US-5292720-A Formate ester indane compounds UNION CAMP CORPORATION (US) 1994-03-08 US disclosed
US-4352748-A Novel acyl-polyalkylindan compounds and the use thereof as a base for perfume, as well as perfume compositions NAARDEN INTERNATIONAL N.V. (NL) 1982-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090238785-A1 Novel Aldehydic Musks and Derivatives Thereof ALDH2, ME2, ALDH3A1 GRIA1 3137/4885GRIA2 3022/4885GRIA3 3154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.